December 2, 2016
Re-Thinking Nicotine and its Effects | Schroeder Institute for Tobacco Research and Policy Studies
In this paper, we broadly synthesize scientific evidence concerning use and effects of nicotine in human populations, and re-examine nicotine’s role in promoting and potentially reducing tobacco-related harms. Tobacco- and nicotine-containing products have evolved considerably in terms of their modes of delivery and corresponding harm potential. When nicotine is delivered in combustible tobacco products (e.g., cigarettes, cigars), addiction and persistent use results in devastating consequences. Less clear are nicotine’s effects when delivered in noncombustible tobacco products and, most recently, in forms that are increasingly separated from toxic tobacco and combustion byproducts. Can such products play a role in an overall tobacco harm reduction and control strategy?